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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2350827Generated: October 31, 2026

Pyridine → HCID 178444512, compound

https://huagongshe.com/reaction/2350827

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
Reactant4-(Trifluoromethyl)phenolHCID 67874—
ReactantHCID 178444510HCID 178444510—
SolventTolueneHCID 1140—
ProductHCID 178444512HCID 178444512—

Reaction Steps

A solution of 29.3 g of trans-4-(trans-4-n-pentylcyclohexyl)-cyclohexanecarbonyl chloride in 120 ml of toluene is added dropwise in the course of 2 hours with stirring to a boiling solution of 16.2 g of p-trifluoromethylphenol and 10 ml of pyridine in 120 ml of toluene. The reaction mixture is refluxed for a further 3 hours and then evaporated. The residue is worked up as conventional. p-Trifluoromethylphenyl trans-4-(trans-4-n-pentylcyclohexyl)-cyclohexanecarboxylate is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04871469
Source datasetuspto-grants-1989_10
ORD IDord-60268e7cfaf6495e975b278cbda7bb30
Source noteuspto-grants-1989_10