Nitric Acid → HCID 19847264, compound

HRID 2350846Notes

Reaction equation

HRID 2350846 reaction equation
[N+:1]([O-:4])(O)=[O:2].[CH2:5]([C:23]1[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22].O>C(O)(=O)C>[N+:1]([C:27]1[CH:28]=[C:23]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH:24]=[CH:25][C:26]=1[OH:29])([O-:4])=[O:2]

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 962WaterHCID 38488794-octadecylphenol

Product 1

HCID 19847264HCID 19847264, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

40 ml of nitric acid (d=1.18) was added dropwise to a solution of 10 g of p-octadecylphenol dissolved in 300 ml of acetic acid at 10° to 40° C. After one hour, the reaction mixture was poured into water, extracted with ethyl acetate, washed with water, then with aqueous sodium bicarbonate solution, followed by drying. After the solvent was evaporated, the residued crystals were recrystallized from n-hexane. 2-Nitro-4-octadecylphenol of m.p. 71° C. was obtained in an amount of 8.4 g.

Workup

  1. extractionextracted with ethyl acetate
  2. washwashed with water
  3. customby drying
  4. customAfter the solvent was evaporated
  5. customthe residued crystals were recrystallized from n-hexane

Sources & evidence

ORD record
ord-ce0babc5713a430a990159a71b057a62
Source dataset
uspto-grants-1989_10
Patent number
US04871655

Reaction notes

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