HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylhydrazine → 10-(dimethylamino)-2,10-dihydroimidazo[2,1-b]quinazolin-5(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylhydrazine | HCID 5976 | — |
| Reactant | 1-(2-Fluorobenzoyl)-2-methylthio-2-imidazoline | HCID 3236905 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Diglyme | HCID 8150 | — |
| Product | 10-(dimethylamino)-2,10-dihydroimidazo[2,1-b]quinazolin-5(3H)-one | HCID 14387120 | 77% |
Reaction Steps
A solution of 2.40 g (10.1 mmoles) of the product of Example 1 and 3 ml of 1,1-dimethylhydrazine in 6 ml of diglyme was heated at 165° C. for 3 hours in a sealed glass tube. Upon cooling, the solution was diluted with water and the resulting solid was collected and air-dried to give 1.80 g of 2,10-dihydro-10-(dimethylamino)imidazo[2,1-b]quinazolin-5(3H)-one. Melting point 197°-198° C. Total yield 77%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04871732 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-3050f37c7df845b0845d71a935234d8d |
| Source note | uspto-grants-1989_10 |