Sodium borohydride → HCID 10561712, compound

Participants

Reaction Steps

A 850 mg (3.6 mmol) sample of the compound from step 43a was dissolved in 20 mL of ethanol and treated with 206 mg (5.4 mmol) of sodium borohydride. The mixture was stirred at room temperature for 1 hour, then quenched with water and extracted with ether. The extract was washed with water, dried over MgSO4, and concentrated in vacuo to give 950 mg of an oil that was taken to the next step without further purification. NMR (CDCl3) δ:7.09 (s, 1H), 4.60 (s, 2H), 2.85 (t, J=7 Hz, 2H), 1.68 (m, 2H), 0.99 (t, J=7 Hz, 3H).

Provenance & Evidence