Benzene → HCID 178505161, compound

Participants

Reaction Steps

42.6 g of 2-methanesulfonylimino-1,3benzodioxole was suspended in 126 ml of methylene chloride. Thereto was dropwise added 31.4 g of 2-[(2furyl)methylthio]ethylamine at 10° to 15° C. Stirring was effected at the same temperature for 30 minutes. The reaction mixture was mixed with 250 ml of benzene and the resulting mixture was stirred at the same temperature for 30 minutes. The crystals deposited were collected by filtration to obtain 65.5 g (yield: 88%) of N-[2-[(2-furyl)methylthio]ethyl]-O-(2-hydroxyphenyl)-N'-methanesulfonylisourea.

Provenance & Evidence