Monochloramine → 4-(2-Chloro-ethyl)-2,6-dimethyl-morpholine hydrochloride

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Reaction Steps

An amount, 389.3 grams, of 2,6-dimethyl-N-(2-hydroxypropyl) morpholine (2.25 moles) was condensed with the free chloroamine obtained from 481.5 grams N-chloroethyl-2,6-dimethylmorpholine hydrochloride (2.25 moles) as described above to give 415.9 grams (58.8%) of the catalyst, bp 127°-129° C. at 0.3 mm of Hg. The structure was confirmed as that of the title compound by elemental analysis, calc. 64.9 C, 10.9 H, 8.9 N; found 64.4 C, 10.6 H, 8.9 N.

Provenance & Evidence