HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2,4,5-Trifluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,4,5-Trifluorobenzoic acid | HCID 521170 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2,4,5-Trifluorobenzoyl chloride | HCID 145164 | — |
Reaction Steps
To 20 ml of anhydrous benzene were added 3.4 g of 2,4,5-trifluorobenzoic acid and 10 ml of thionyl chloride, and the mixture was refluxed for 2 hours. After removing the solvent, excess thionyl chloride was removed three times as an azeotropic mixture with benzene to obtain 2,4,5-trifluorobenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04871852 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-50ca50940337487cba1a30e5b9921a5c |
| Source note | uspto-grants-1989_10 |