(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → HCID 14061412, compound

Participants

Reaction Steps

Using Saccharomyces uvarum IFO 1225 cultivated similarly to Example 3, and 504 mg of (1SR,5RS)-2- ethoxycarbonyl-7,7-ethylenedioxybicyclo[3.3.0]octan-3-one (VIII), reaction was initiated in a similar procedure as mentioned in Referential Example 3. 10 g of glucose after 4 hours, 5 g after 19 hours, and 10 g after 153 hours were added and shaken for 167 hours. Aftertreatment of the reaction mixture in a similar manner as described in Example 3 gave 101 mg of (1S,5R)-2-ethoxycarbonyl-7,7-ethylenedioxybicyclo[3.3.0]octan-3-one (IV).

Provenance & Evidence