(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → HCID 14061412, compound

Participants

Reaction Steps

Using Saccharomyces carlsbergensis IFO 0565 cultivated similarly to Example 3 and 500 mg of (1SR,5RS)-2-ethoxycarbonyl-7,7-ethylenedioxybicyclo[3.3.0]octan-3-one (VIII), reaction was initiated in a similar manner as described in Referential Example 3. 10 g of glucose after 4 hours and 10 g after 23 hours were added and shaken for 68 hours. Aftertreatment of a reaction mixture in a similar manner as described in Referential Example 3 gave 219 mg of (1S,5R)-2-ethoxycarbonyl-7,7-ethylenedioxybicyclo[3.3.0]- octan-3-one (IV).

Provenance & Evidence