Triethylamine → HCID 23353501, compound

Participants

Reaction Steps

The title product was prepared following the procedure of example 3 from 7- amino-1-(4-methylol-piperazinyl)-naphthalene (0.15 g, 0.622 mmol) and triethylamine (0.09 mL, 0.68 mmol) and 3-nitrobenzoyl chloride (0.127 mL, 0.684 mmol) in acetonitrile (10 mL) with an overnight reflux. The product was purified by silica gel flash chromatography followed by recrystallization from ethyl acetate to yield 0.116 g (47%) of the title product: mp 182°-184° C. Analysis calculated for C22H22N4O3 : C, 67.68; H, 5.68; N, 14.35. Found: C, 67.47; H, 5.64; N, 14.08.

Provenance & Evidence