Potassium Hydroxide → HCID 19845475, compound

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Reaction Steps

A mixture of 100 ml of ethanol, 7.8 g of potassium hydroxide and 35.0 g of ethyl 5-benzylthio-1,3-dimethyl-pyrazole-4-carboxylate obtained in Reference Example 5 is refluxed while stirring for 5 hours. After evaporating off ethanol, dichloromethane is added to the residue, and the resulting solution is extracted with water. After acidifying the aqueous solution to pH 2 with diluted hydrochloric acid, extracted with dichloromethane, and then dried over anhydrous sodium sulfate. Evaporating off dichloromethane yields 27.7 g of the title compound.

Provenance & Evidence