Pyridine → HCID 54333914, compound

Participants

Reaction Steps

To 50 ml of pyridine is added 4.3 g of N-(1,3-dimethyl-4-methoxycarbonyl-5-pyrazolesulfonyl)-N'(4,6-dimethoxy-2-pyrimidinyl)thiourea, and to the mixture is added 1.6 g of bromine while cooling at -6° C. to -8° C. After stirring at the same temperature for 1.5 hours, the reaction mixture is poured into 300 ml of water. The resulting crystals are filtered, washed with water, and dried. Recrystallization from acetonitrile gives 2.8 g of the title compound as colorless crystals

Provenance & Evidence