Bromine → HCID 54019409, compound

Participants

Reaction Steps

0 g of potassium salt of N-(4-ethoxycarbonyl-1-methyl-5-pyrazolesulfonyl)-N'-(4,6-dimethoxy-2-pyrimidinyl)thiourea (acetonitrile-solvate product) is dissolved in 20 ml of pyridine, and to the solution is added dropwise 0.37 g of bromine while cooling at -6° C. to -8° C. The reaction mixture is stirred at the same temperature for 2 hours, and poured into 100 ml of ice water. The resulting crystals are filtered, washed with water, and recrystallized from acetonitrile to give 0.5 g of the title compound as colorless crystals.

Provenance & Evidence