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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2351251Generated: October 26, 2026

Aniline → Aniline, N-(2,2,2-trifluoroethyl)-

https://huagongshe.com/reaction/2351251

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
ReactantHCID 10993805HCID 10993805—
SolventDichloromethaneHCID 6344—
ProductAniline, N-(2,2,2-trifluoroethyl)-HCID 959690.8%

Reaction Steps

250 mg (0.573 mmol) of (2,2,2-trifluoroethyl)phenyliodonium trifluoromethanesulfonate, 107 mg (1.15 mmol) of aniline and 5 ml of methylene chloride were reacted and worked up in the same manner as described in Reference Example 4 to obtain 91.1 mg of N-(2,2,2-trifluoroethyl)aniline as an oily substance. Yield, 92%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04873027
Source datasetuspto-grants-1989_10
ORD IDord-5d456a4c84e6411aa1338919de3e5b1a
Source noteuspto-grants-1989_10