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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2351252Generated: November 1, 2026

N-Ethylaniline → N-ethyl-N-(2,2,2-trifluoroethyl)aniline

https://huagongshe.com/reaction/2351252

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-EthylanilineHCID 7670—
ReactantHCID 10993805HCID 10993805—
SolventDichloromethaneHCID 6344—
ProductN-ethyl-N-(2,2,2-trifluoroethyl)anilineHCID 1351011198%

Reaction Steps

203 mg (0.465 mmol) of (2,2,2-trifluoroethyl)phenyliodonium trifluoromethanesulfonate, 113 mg (0.931 mmol) of N-ethylaniline and 5 ml of methylene chloride were treated and worked up in the same manner as described in Reference Example 4 to obtain 92.6 mg of N-ethyl-N-(2,2,2-trifluoroethyl)aniline as an oily substance. Yield, 98%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04873027
Source datasetuspto-grants-1989_10
ORD IDord-00303ec1727f4327b70951890f3853b8
Source noteuspto-grants-1989_10