Aniline → N,N-bis(2,2,2-trifluoroethyl)aniline

Participants

Reaction Steps

310 mg (1.49 mmol) of 2,6-di-tert-butyl-4-methylpyridine was added to a solution of 654 mg (1.49 mmol) of (2,2,2-trifluoroethyl)phenyliodonium trifluoromethanesulfonate in 5 ml of methylene chloride in an argon atmosphere at room temperature, and then 46 mg (1.49 mmol of aniline was added to the mixture. After stirring for 2 hours at room temperature for 2 hours, the mixture was worked up in the same manner as described in Reference Example 4 to obtain 119 mg (94%) of N,N-bis(2,2,2-trifluoroethyl)aniline.

Provenance & Evidence