HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylhydrazine → cis-1,2,2a,3,4,9-hexahydro-9bH-cyclobuta[a]carbazole-9b-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylhydrazine | HCID 7516 | — |
| Reactant | cis-2-Oxobicyclo[4.2.0]octane-1-acetic acid ethyl ester | HCID 53960823 | — |
| Product | cis-1,2,2a,3,4,9-hexahydro-9bH-cyclobuta[a]carbazole-9b-acetic acid ethyl ester | HCID 86742523 | 16.6% |
Reaction Steps
cis-2-Oxobicyclo[4.2.0]octane-1-acetic acid ethyl ester (3.5 g, 17.01 mmol) and phenylhydrazine (1.9 mL, 18.8 mmol) were allowed to react according to the procedure of Example 2. Flash chromatography (SiO2, 10% EtOAC/petroleum ether) afforded 0.798 g (16%) of cis-1,2,2a,3,4,9-hexahydro-9bH-cyclobuta[a]carbazole-9b-acetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04873257 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-e2586ed479414338aadbc6a4cf773840 |
| Source note | uspto-grants-1989_10 |