HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropyl Ether → 5-[[[3-[2-[(Diethylamino)methyl]-piperidin-1-yl]propyl]amino]carbonyl]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropyl Ether | HCID 7914 | — |
| Reactant | 5-chlorocarbonyl-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one | HCID 13276745 | — |
| Reactant | 3-[2-[(Diethylamino)methyl]-piperidin-1-yl]propanamine | HCID 14210001 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-[[[3-[2-[(Diethylamino)methyl]-piperidin-1-yl]propyl]amino]carbonyl]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one | HCID 14210075 | 54% |
Reaction Steps
Prepared analogously to Example 2 from 5-chlorocarbonyl-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one and 3-[2-[(diethylamino)methyl]-piperidin-1-yl]propanamine in a yield of 54% of theory, m.p. 148.0°-149.5° C. (diisopropylether). Soluble in water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04873236 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-3ea14e7a86624a77806c869edbd6554b |
| Source note | uspto-grants-1989_10 |