Methanol → HCID 15671137, compound

HRID 2351520Notes

Reaction equation

HRID 2351520 reaction equation
[CH3:1][C:2]1([CH2:14][O:15][C:16]2[CH:21]=[CH:20][C:19]([N+:22]([O-])=O)=[CH:18][CH:17]=2)[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][C:6]([CH3:13])=[CH:7][C:8]=2[CH3:12])[O:3]1.CO>[Pd].C1C=CC=CC=1>[NH2:22][C:19]1[CH:20]=[CH:21][C:16]([O:15][CH2:14][C:2]2([CH3:1])[CH2:11][CH2:10][C:9]3[C:4](=[CH:5][C:6]([CH3:13])=[CH:7][C:8]=3[CH3:12])[O:3]2)=[CH:17][CH:18]=1

Participants

5

Reactant 2

HCID 887MethanolHCID 15671133HCID 15671133, compound

Product 1

HCID 15671137HCID 15671137, compoundYield 75%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 241BenzeneSolvent

Procedure

Following a procedure similar to that described in Preparation 4, 2.1 g of 2,5,7-trimethyl-2-(4-nitrophenoxymethyl)-2H-chromene (prepared as described in Preparation 25) were hydrogenated at atmospheric pressure, using 200 mg of 10% w/w/ palladium-on-carbon, 20 ml of methanol and 50 ml of benzene, to afford 1.44 g of the title compound.

Sources & evidence

ORD record
ord-fac5e02ed81d4570a4386a3b03bd8aee
Source dataset
uspto-grants-1989_10
Patent number
US04873255

Reaction notes

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