HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 15613919, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 1-(4-Nitrophenoxy)propan-2-one | HCID 308507 | — |
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | 3-Acetyl-4-hydroxybenzoic acid | HCID 9179245 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 15613919 | HCID 15613919 | 88.7% |
Reaction Steps
A procedure similar to that described in Preparation 1 was repeated, except that 10 g of 3-acetyl-4-hydroxybenzoic acid, 13 g of 4-nitrophenoxyacetone, 7.9 g of pyrrolidine, 2.6 g of p-toluenesulfonic acid monohydrate and 150 ml of benzene were reacted, to afford 17.6 g of the title compound as pale brown crystals, melting at 227°-235° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04873255 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-34429053a693483fb9427a74a74b96e0 |
| Source note | uspto-grants-1989_10 |