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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2351705Generated: November 2, 2026

N-Methylbenzylamine → HCID 14390318, compound

https://huagongshe.com/reaction/2351705

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylbenzylamineHCID 7669—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 15617192HCID 15617192—
SolventTetrahydrofuranHCID 8028—
ProductHCID 14390318HCID 14390318—

Reaction Steps

Under nitrogen bubbling, a mixture of 2-(4-trifluoromethyl-phenyl)-3H-imidazo [4,5-b]pyridine-3-acetic acid (3.21 g, 0.01 mole) and 1,1'-carbonyldiimidazole (1.62 g, 0.01 mole) in 150 ml of tetrahydrofuran was stirred at room temperature for 3 hrs. N-methylbenzylamine (1.33 g, 0.011 mole) was added, and the reaction mixture was allowed to stir at room temperature for 1 hr.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04873251
Source datasetuspto-grants-1989_10
ORD IDord-6c9df43015f74f1d8a357944dbd2ce47
Source noteuspto-grants-1989_10