Hydrochloric Acid → HCID 23037408, compound

Participants

Reaction Steps

A solution of crude 2-(4-chlorophenyl)-N-[2-(diethylamino) ethyl]-3H-imidazo[4,5-b]pyridine-3-acetamide (3.21 g, 0.0112 mole) in hot isopropyl alcohol was treated with ethereal hydrogen chloride until acidic. The solution was evaporated to dryness, the residue dissolved in hot isopropyl alcohol and the solution was filtered while hot. Solid precipitated upon cooling to room temperature. Isopropyl ether was added and the solid was collected by filtration and rinsed with isopropyl ether. The solid was dried under high vacuum to give 4.4 g (84%) of title compound, mp. 193°-196° C.

Provenance & Evidence