Hydrochloric Acid → HCID 23037422, compound

Participants

Reaction Steps

A solution of crude 2-(4-chlorophenyl)-N-[2-(dimethylamino)-ethyl ]-N-methyl-3H-imidazo[4,5-b]pyridine-3-acetamide (2.5 g, 0.0067 mole) in hot isopropyl alcohol was treated with hydrogen chloride in isopropyl alcohol until the solution was acidic. Upon addition of isopropyl ether, solid precipitated. After cooling to room temperature, the solid was collected by filtration, rinsed with isopropyl ether, and dried under high vacuum to give 2.23 g (75%) of title compound, mp 239°-242° C.

Provenance & Evidence