Hydrochloric Acid → HCID 54457196, compound

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Reaction Steps

Analogous to this formula, 5.8 g=95.1% of the theoretical yield or 2.4 g=80.0% of the theoretical yield of 4-aminobenzyl-benzylcyanide is prepared from 7.0 g or 3.4 g of 4-nitrobenzyl-benzylcyanide, with 6.1 or 3.0 g of tin, 95.4 ml or 46.3 ml of ethanol and 27.7 ml or 13.5 ml of hydrochloric acid, 32%. The two raw products are combined and chromatographed (silica gel 0.063-0.2 mm, developing agent diethyl ether: petroleum ether--2:1).

Provenance & Evidence