Ethyl bromoacetate → 2-Bromo-N,N-diethylethanamine

HRID 2351876Notes

Reaction equation

HRID 2351876 reaction equation
C(O[C:4](=[O:7])[CH2:5][Br:6])C.[CH2:8]([N:10]([CH2:15][CH3:16])[C:11](=[O:14])[CH2:12][Br:13])[CH3:9]>>[CH2:8]([N:10]([CH2:11][CH2:12][Br:13])[CH2:15][CH3:16])[CH3:9].[C:11]([NH:10][C:4](=[O:7])[CH2:5][Br:6])(=[O:14])[CH3:12]

Participants

4

Reactant 2

HCID 7748Ethyl bromoacetateHCID 2255452-bromo-N,N-diethylacetamide

Product 2

HCID 706082-Bromo-N,N-diethylethanamineHCID 22616025N-Acetyl-2-bromoacetamide

Procedure

When ethylbromoacetate in the above procedure is replaced with N,N-diethyl-α-bromoacetamide; N,N-diethylaminoethyl bromide or N-acetyl-α-bromoacetamide, then the corresponding products are obtained.

Sources & evidence

ORD record
ord-72040956a871443aa62f6e5b305708c4
Source dataset
uspto-grants-1989_10
Patent number
US04874769

Reaction notes

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