HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2351895Generated: November 1, 2026
HCID 15631820, compound → 3,4-Difluoro-2-methylaniline
https://huagongshe.com/reaction/2351895
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 15631820 | HCID 15631820 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3,4-Difluoro-2-methylaniline | HCID 14738849 | 117.7% |
Reaction Steps
Into a solution of 6-bromo-3,4-difluoro-2-methylthiomethylaniline (6.00 g) in ethanol (120 ml) is suspensed Raney nickel (70 ml), and the mixture is stirred at 50° C. for 30 minutes. After removing Raney nickel by filtration, the filtrate is concentrated to give 3,4-difluoro-2-methylaniline (3.77 g) as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04874764 |
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| Source dataset | uspto-grants-1989_10 |
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| ORD ID | ord-923cca1aaf9448c1becb43324453e700 |
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| Source note | uspto-grants-1989_10 |
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