HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Bis(4-fluorophenyl)prop-2-en-1-one → 1,3-Bis(4-fluorophenyl)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Bis(4-fluorophenyl)prop-2-en-1-one | HCID 244229 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1,3-Bis(4-fluorophenyl)propan-1-one | HCID 19844956 | — |
Reaction Steps
A solution of 59.9 g of 4,4'-difluorobenzylideneacetophenone in 600 ml of tetrahydrofuran is hydrogenated in the presence of 6 g of Raney nickel. After removal of the catalyst, the reaction mixture is concentrated by rotary evaporation, affording the title compound of the formula ##STR8## as a crude product with a refractive index of n20D =1.5478.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04874778 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-5e902176a6434dc5872890f0acd6852a |
| Source note | uspto-grants-1989_10 |