Ammonia → HCID 55285407, compound

HRID 2351947Notes

Reaction equation

HRID 2351947 reaction equation
[CH:1]1([NH:4][C:5](=[O:10])[CH2:6][C:7]([CH3:9])=O)[CH2:3][CH2:2]1.[NH3:11]>C(O)C>[CH:1]1([NH:4][C:5](=[O:10])/[CH:6]=[C:7](\[NH2:11])/[CH3:9])[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 222Ammonia2×HCID 14627908HCID 14627908, compound

Product 1

HCID 55285407HCID 55285407, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Acetoacetic cyclopropylamide (209.4 g, 1.48 mole) is dissolved in ethanol (160 ml) and thereto is passed ammonia gas, while the temperature is controlled below 30° C. by cooling with a water bath. After passing ammonia gas for about 3 hours, yellow crystals precipitate. The reaction mixture is allowed to stand at 0° C. overnight. The precipitates are separated by filtration and washed with diethyl

Workup

  1. customis controlled below 30° C.
  2. temperatureby cooling with a water bath
  3. customfor about 3 hours
  4. customThe precipitates are separated by filtration
  5. washwashed with diethyl

Sources & evidence

ORD record
ord-7b6a396e5e87409abc9bf54f78e78f14
Source dataset
uspto-grants-1989_10
Patent number
US04874773

Reaction notes

Loading…