反应详情

To a suspension of 20.0 g of methyl 4-[4-(phenylacetyl)phenyl]butyrate in 200 ml of methanol, 2.52 g of sodium borohydride was added portionwise under ice-cooling, and stirring was continued for 1 hour. After the reaction solvent was removed under reduced pressure, the residue was added with water and then extracted with ether. After the ether layer was washed with water and dried, the solvent was removed to yield 20.3 g of pale yellow oil.

1. additionwas added portionwise under ice-
2. temperaturecooling
3. customAfter the reaction solvent was removed under reduced pressure
4. additionthe residue was added with water
5. extractionextracted with ether
6. washAfter the ether layer was washed with water
7. customdried
8. customthe solvent was removed