HCID 681060, compound → HCID 506617, compound

HRID 2351996Notes

Reaction equation

HRID 2351996 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[CH:9][C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)=[CH:4][CH:3]=1.[H][H]>[Pd].C(O)C>[OH:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][CH2:9][C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)=[CH:6][CH:7]=1

Participants

5

Reactant 2

HCID 681060HCID 681060, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 506617HCID 506617, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Five g. of 3-(4-hydroxyphenyliminomethyl)pyridine was prepared according to the process of Preparation 1, and was dissolved in 50 ml. of ethanol. One g. of palladium on carbon hydrogenation catalyst was added, and the mixture was agitated under 40 psig. hydrogen pressure for 1 hour. The catalyst was then removed by filtration, and the filtrate was evaporated to dryness. The residue consisted in large part of the desired intermediate product.

Workup

  1. customaccording to the process of Preparation 1
  2. dissolutionwas dissolved in 50 ml
  3. customThe catalyst was then removed by filtration
  4. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-9d688e6413bb4bef9fbe8913e534d753
Source dataset
uspto-grants-1989_10
Patent number
US04874775

Reaction notes

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