Toluene → HCID 19844949, compound

Participants

Reaction Steps

A 3.2 g. portion of 3-(3-nitrophenylaminomethyl)pyridine was dissolved in 15 ml. of toluene, and 2.7 g. of potassium carbonate and 1.6 ml. of methanesulfonyl chloride were added. The mixture was heated to a gentle boil and stirred overnight under reflux. Twenty-five ml. of water and 25 ml. of ethyl acetate were added, and the organic phase was dried and evaporated under vacuum. The residue was triturated with diethyl ether, filtered and dried to obtain 2.4 g. of the desired product, m.p. 131°-133°.

Provenance & Evidence