Hippuric Acid → Acetyl chloride, (benzoylamino)-

HRID 2352042Notes

Reaction equation

HRID 2352042 reaction equation
[C:1]([OH:13])(=O)[CH2:2][NH:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5].P(Cl)(Cl)(Cl)(Cl)[Cl:15]>C(Cl)(=O)C>[C:1]([Cl:15])(=[O:13])[CH2:2][NH:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5]

Participants

4

Reactant 2

HCID 464Hippuric AcidHCID 24819Phosphorus pentachloride

Product 1

HCID 11356064Acetyl chloride, (benzoylamino)-

Reagents, catalysts & solvents 1

HCID 6367Acetyl chlorideSolvent

Procedure

The title compound was prepared by the chlorination of hippuric acid using phosphorus pentachloride in acetyl chloride according to a literature procedure, mp 124°-126° C. dec (McInally, I. et al J. Polymer Sci. Polymer Chem. Ed. (1977), 15, 2511, mp 125° C. dec.).

Sources & evidence

ORD record
ord-db1fea6af0af47e0aeac6fe89421de1a
Source dataset
uspto-grants-1989_10
Patent number
US04874876

Reaction notes

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