3-Chloro-N,N-dimethyl-1-propanamine → HCID 14347185, compound

HRID 2352170Notes

Reaction equation

HRID 2352170 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:12]=[CH:11][N:10]=[C:9]([NH:13][C:14]3[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=3)[N:8]=2)=[CH:3][CH:2]=1.[CH3:21][N:22]([CH3:27])[CH2:23][CH2:24][CH2:25]Cl>>[CH3:21][N:22]([CH3:27])[CH2:23][CH2:24][CH2:25][O:20][C:17]1[CH:18]=[CH:19][C:14]([NH:13][C:9]2[N:8]=[C:7]([C:4]3[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=3)[CH:12]=[CH:11][N:10]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 669603-Chloro-N,N-dimethyl-1-propanamineHCID 135804947HCID 135804947, compound

Product 1

HCID 14347185HCID 14347185, compound

Procedure

A 2.78 g portion of 4-[[4-(4-pyridinyl)-2-pyrimidinyl]amino]phenol and 2.35 g of 3-dimethylaminopropyl chloride were reacted as described in Example 255, giving 850 mg of the desired product, mp 123°-124.5° C.

Sources & evidence

ORD record
ord-8b53e6b144124848a0961bb4521c6134
Source dataset
uspto-grants-1989_10
Patent number
US04876252

Reaction notes

Loading…