HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 14346971, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(4-(Pyridin-3-yl)pyrimidin-2-ylamino)benzoic acid | HCID 14346970 | — |
| Product | HCID 14346971 | HCID 14346971 | — |
Reaction Steps
A 5.85 g portion of 4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid in 30 ml of thionyl chloride was refluxed on a steam bath for one hour, then evaporated to dryness. The residue was boiled with dimethoxyethane, then cooled and the solid recovered and washed with ether, giving 6.90 g of 4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04876252 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-1006f92095d34e958488342db5f504eb |
| Source note | uspto-grants-1989_10 |