HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2352197Generated: November 1, 2026
Hexanoic Acid → 4,4-Dimethyl-2-pentyl-4,5-dihydro-1,3-oxazole
https://huagongshe.com/reaction/2352197
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hexanoic Acid | HCID 8892 | — |
| Reactant | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Product | 4,4-Dimethyl-2-pentyl-4,5-dihydro-1,3-oxazole | HCID 12325558 | 81.2% |
Reaction Steps
Following the procedure under Example 11, 6.085 g (52.4 mmoles) of hexanoic acid and 10 ml (9.34 g, 104.8 mmoles) of 2-amino-2-methylpropanol was heated to 185°C. Work up and fractional distillation gave 7.2g (81%) of product, b.p. 90°-92° C./25mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04876249 |
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| Source dataset | uspto-grants-1989_10 |
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| ORD ID | ord-6cc3f251a01e4e1ab379b4fc718c2f48 |
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| Source note | uspto-grants-1989_10 |
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