反应详情

22.84 g. (100 mmoles) of ethyl laurate and 15.34 g. (118 mmoles) of Nl -isopropyl-2-methyl-1,2-propanediamine is heated at 130°-230° C. until approximately 100 mmoles of ethanol is collected. Toluene is then cautiously added and the heating is continued until no more water separates. The solution is acidified, the aqueous layer is separated and basified with NaOH. This is extracted with ethyl acetate, the organic extract is dried and concentrated. The oil is distilled at 150-152° C./1.2 mm to give 16.74 g (58%) of product.

1. customis collected
2. additionToluene is then cautiously added
3. customthe aqueous layer is separated
4. extractionThis is extracted with ethyl acetate
5. extractionthe organic extract
6. customis dried
7. concentrationconcentrated
8. distillationThe oil is distilled at 150-152° C./1.2 mm