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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2352238Generated: October 25, 2026

Benzenesulfonamide, 4-methyl-N-phenyl- → N-[4-[(1-acetyl-4-piperidinyl)carbonyl]phenyl]Methanesulfonamide

https://huagongshe.com/reaction/2352238

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenesulfonamide, 4-methyl-N-phenyl-HCID 2456—
Reactant1-Acetylpiperidine-4-carbonyl chlorideHCID 100950—
ReactantN-benzoylnipecotoyl chlorideHCID 15718173—
ProductN-[4-[(1-acetyl-4-piperidinyl)carbonyl]phenyl]MethanesulfonamideHCID 14130038—

Reaction Steps

The same procedure as above was repeated except that methanesulfonamilide was replaced with p-toluenesulfonanilide or 1-acetylisonipecotoyl chloride was replaced with (±-N-benzoylnipecotoyl chloride or (±)-N-benzoyl-β-prolyl chloride prepared in Referential Example 2 to obtain the following compounds:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04876262
Source datasetuspto-grants-1989_10
ORD IDord-db275786a012421c8bfd0578dc1483af
Source noteuspto-grants-1989_10