HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2352327Generated: November 2, 2026
alpha,alpha,alpha-Trifluoro-3,5-dinitrotoluene → 5-(Trifluoromethyl)benzene-1,3-diamine
https://huagongshe.com/reaction/2352327
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | alpha,alpha,alpha-Trifluoro-3,5-dinitrotoluene | HCID 123060 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(Trifluoromethyl)benzene-1,3-diamine | HCID 67781 | 91% |
Reaction Steps
A 24.8 g sample of 3,5-dinitrobenzotrifluoride purchased from Aldrich Chemical Co. was slurried in 200 ml of ethanol and 5 g of 1% palladium on carbon added. This mixture was transferred to an autoclave, pressured to 400 psi with hydrogen, and heated at 75° C. with stirring for 1 hr. A 91% yield of pure 3,5-diaminobenzotrifluoride was recovered.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04876329 |
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| Source dataset | uspto-grants-1989_10 |
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| ORD ID | ord-5a4f0008d0d44c0280f0433623697b67 |
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| Source note | uspto-grants-1989_10 |
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