Pyridine → 2-(2-Methyl-1,3-dioxolan-2-yl)acetaldehyde

HRID 2352384Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2352384
N1C=CC=CC=1.[CH2:7]1[CH2:15][O:14][C:9]([CH2:11][CH2:12][OH:13])([CH3:10])[O:8]1>ClCCl>[CH2:7]1[CH2:15][O:14][C:9]([CH3:10])([CH2:11][CH:12]=[O:13])[O:8]1

Komponenten

4

Edukt 2

HCID 1049PyridineHCID 5383821,3-Dioxolane-2-ethanol, 2-methyl-

Produkt 1

HCID 110079262-(2-Methyl-1,3-dioxolan-2-yl)acetaldehydeAusbeute 70,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Reaktionsbedingungen

Temperatur
20 °C

Versuchsvorschrift

Pyridine (7.2 g) and chromic oxide (CrO3) (4.6 g) are added in small fractions to dichloromethane (150 cc) over 10 minutes. After 15 minutes' stirring at a temperature in the region of 20° C., 2,2-ethylenedioxy-4-hydroxybutane (0.85 g, 6.4 mmol) is added quickly as a solution in dichloromethane (2 cc). After 15 minutes' stirring at 20° C., the black, viscous precipitate is separated off by filtration through silica and is washed with ether. After evaporation of the solvents, 3,3-ethylenedioxybutanal (0.59 g) is obtained (B.P.0.4 =35° C.).

Aufarbeitung

  1. customthe black, viscous precipitate is separated off by filtration through silica
  2. washis washed with ether
  3. customAfter evaporation of the solvents

Quellen und Nachweise

ORD-Eintrag
ord-10deac69eafb4421b9465974b7cf6245
Quelldatensatz
uspto-grants-1989_10
Patentnummer
US04876370

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