HCID 14819130, compound → HCID 14819133, compound

Participants

Reaction Steps

Dissolved in 100 ml of methanol was 3.75 g of Isomer BCD of N-(2-oxo-5-octyl-3-tetrahydrofuranyl)-L-alanine benzyl ester. Thereafer, 0.70 g of 10% palladium-charcoal was added and the reaction mixture was hydrogenated at room temperature and normal pressure for 2 hours. The palladium-charcoal was then filtered off and the filtrate was distilled under reduced pressure to obtain crystals. The crystals were recrystallized from methanol, thereby obtaining 2.41 g of Isomer BCD of N-(2-oxo-5-octyl-3-tetrahydrofuranyl)-L-alanine as colorless crystals.

Provenance & Evidence