Imidazole → HCID 178432030, compound
Reaction equation
N1C=CN=C1.[F:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[N:14]=[C:15]([CH3:26])[N:16](O)[C:17]=2[C:18]2[CH:23]=[CH:22][NH:21][C:20](=[O:24])[CH:19]=2)=[CH:9][CH:8]=1>>[F:6][C:7]1[CH:12]=[CH:11][C:10]2=[C:13]3[N:14]=[C:15]([CH3:26])[NH:16][C:17]3=[C:18]3[C:19]([C:20](=[O:24])[NH:21][CH:22]=[CH:23]3)=[C:9]2[CH:8]=1Participants
3
Procedure
The title compound was prepared as a mixture of imidazole tautomers from 4-[4-(4-fluorophenyl)-1-hydroxy-2-methyl-1H-imidazol-5-yl]pyridin-2(1H)-one (EXAMPLE 8, Step A) following the procedure described in EXAMPLE 1, Step E.
Sources & evidence
- ORD record
- ord-c06c6a163ccd4113804df643779a31a6
- Source dataset
- uspto-grants-2005_02
- Patent number
- US06852727B2
Reaction notes
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