Potassium Hydroxide → HCID 86743479, compound

HRID 2352408Notes

Reaction equation

HRID 2352408 reaction equation
[OH-].[K+].C([O:5][C:6]([C:8]1[CH:26]=[CH:25][C:11]([C:12]([CH3:24])=[CH:13][C:14]2[CH:23]=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:15]=2)=[CH:10][CH:9]=1)=[O:7])C>O.C(O)C>[C:6]([C:8]1[CH:9]=[CH:10][C:11]([C:12]([CH3:24])=[CH:13][C:14]2[CH:23]=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:15]=2)=[CH:25][CH:26]=1)([OH:7])=[O:5]

Participants

5

Reactant 2

HCID 14797Potassium HydroxideHCID 86743478HCID 86743478, compound

Product 1

HCID 86743479HCID 86743479, compoundYield 76.8%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

10 g of potassium hydroxide are dissolved in 50 cm3 of water and 200 cm3 of ethanol. 10 g of the compound prepared in Example 7 are added and the reaction mixture is heated under reflux for one hour, cooled and then acidified. The precipitate is filtered off and the insoluble matter is recrystallised from acetic acid. 7 g of the expected product are obtained.

Workup

  1. temperaturethe reaction mixture is heated
  2. temperatureunder reflux for one hour
  3. temperaturecooled
  4. filtrationThe precipitate is filtered off
  5. customthe insoluble matter is recrystallised from acetic acid

Sources & evidence

ORD record
ord-fd26b621653f40e49dea63a66ce98876
Source dataset
uspto-grants-1989_10
Patent number
US04876381

Reaction notes

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