O-Phenylenediamine → HCID 178419356, compound

HRID 235257Notes

Reaction equation

HRID 235257 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4](=O)[C:5](=O)[NH:6]2.[C:13]1([NH2:20])[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[NH2:19]>C(O)(=O)C>[Br:1][C:2]1[C:3]2[C:4]3[C:5]([NH:19][C:14]4[C:13]([N:20]=3)=[CH:18][CH:17]=[CH:16][CH:15]=4)=[N:6][C:7]=2[CH:8]=[CH:9][CH:10]=1

Participants

4

Reactant 2

HCID 7243O-PhenylenediamineHCID 45000124-Bromoisatin

Product 1

HCID 178419356HCID 178419356, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 3.40 g (15.0 mmol) of 4-bromoisatin and 1.63 g (1 eq.) of 1,2-phenylenediamine in 50 ml of acetic acid was refluxed for 2 hours. The reaction solution was allowed to stand at room temperature for 16 hours, and the resulting precipitate was collected by filtration to give 10-bromoindolo[2,3-b]quinoxaline.

Workup

  1. filtrationthe resulting precipitate was collected by filtration

Sources & evidence

ORD record
ord-1b3466bce9cb4e548459e6c9801d9477
Source dataset
uspto-grants-1997_01
Patent number
US05597921

Reaction notes

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