HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hexanethiol → HCID 53796704, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hexanethiol | HCID 8106 | — |
| Reactant | Methyl propiolate | HCID 13536 | — |
| Catalyst | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Product | HCID 53796704 | HCID 53796704 | — |
Reaction Steps
To a cooled (5°) solution of methyl propiolate (1.96 g, 23.0 mmol) is added 2 drops of DBU. 1-Hexanethiol (2.5 g, 21.0 mmol) is then added over a period of 3 minutes. The ice bath is removed, and the reaction mixture is stirred at RT for 1.5 hours. It is then purified by prep. TLC (preparative thin layer chromatography) to give methyl 3-hexylthio-2-propenoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04877899 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-ea991096c20845bea110b11d58368d9f |
| Source note | uspto-grants-1989_10 |