Sodium Hydroxide → HCID 14821669, compound

Participants

Reaction Steps

To a solution of (E)-3-fluoro-3-hexylsulfinyl-2propenyl acetate (3.0 g, 12.0 mmol) in 20 ml of methanol under N2 is added aqueous sodium hydroxide (3.0 g, 37.5 mmol). After 30 min. at RT, the solution is diluted with water and extracted with ether. The aqueous phase is diluted with saturated brine and extracted again with ether. The combined ether extracts are dried over Na2SO4 and stripped to give (E)-3-fluoro-3-hexylsulfinyl-2-propenol (cpd. 2, Table A).

Provenance & Evidence