Pyridine → HCID 14821670, compound

Participants

Reaction Steps

To a mixture of (E)-3-fluoro-3-hexylsulfinyl-2-propenol (0.21 g, 1.0 mmol) and 2 ml of pyridine cooled to -30° is added through syringe acetic-formic anhydride (0.4 ml). The mixture is allowed to warm to 10° over a period of 1 hour. It is then diluted with water, extracted with hexane, washed with aqueous 2N H2S04, then water, then aqueous NaHCO3, finally brine and is dried. The product is purified by prep. TLC to give (E)-3-fluoro-3-hexylsulfinyl-2-propenyl formate (cpd. 3, Table A).

Provenance & Evidence