HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Octanethiol → HCID 86743490, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Octanethiol | HCID 8144 | — |
| Reactant | Methyl but-2-ynoate | HCID 141019 | — |
| Catalyst | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 86743490 | HCID 86743490 | — |
Reaction Steps
Two drops of DBU is added to methyl 2-butynoate (6.0 g) under N2. 1-Octanethiol (8.96 g, 61.2 mmol) is added dropwise over 20 min. with cooling with an ice bath. The mixture is allowed to come to RT and is stirred overnight. It is then diluted with ether, washed, dried and stripped and the product is purified by prep. TLC to give methyl (E)-3-octylthio-2butenoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04877899 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-a1f4ba846bd343b191d9867d50e08f87 |
| Source note | uspto-grants-1989_10 |