Sodium Sulfate → HCID 53639050, compound

Participants

Reaction Steps

M-chloroperbenzoic acid (85%; 0.15 g, 0.75 mmol) is added to a solution of the above fluoropropenyl acetate (0.20 g, 0.75 mmol) in 3 ml of methylene chloride at 5°. The mixture is stirred for 15 min. and is then worked up with aq. Na2SO4 and sat'd aq. NaHCO3, washed with brine and stripped of solvent to give 3-fluoro-3-(6-methoxyhexylsulfinyl)-2-propenyl acetate. The product is purified by prep. TLC on silica gel eluting with 50% ethyl acetate/hexane. The upper band is collected to give (E)-3-fluoro-3-(6-methoxyhexylsulfinyl)-2-propenyl acetate (cpd. 10, Table A).

Provenance & Evidence