Potassium Acetate → ethyl 1-acetyl-4-oxocyclohexane-1-carboxylate

Participants

Reaction Conditions

Reaction Steps

To a stirred suspension of Step 2 product (1 eq) in acetic anhydride (2.5 v/w) under nitrogen was added potassium acetate (0.02 eq). The reaction mixture was heated to, and stirred at the reflux temperature (145° C.) for 2 hours. The resultant solution was concentrated in vacuo, and purged with toluene to afford a brown oil.

Provenance & Evidence