Sodium Hydroxide → HCID 58902525, compound

Participants

Reaction Steps

The title compound (80 mg, 92.3%) was prepared from 4-[4-(4-phenylamino-phenyl)-piperazin-1-yl]-butyric acid methyl ester (86 mg, 0.24 mmol) and 1 N NaOH (0.25 mL, 0.25 mmol) by the procedure described in Example 2: MS (ESI) m/z 361 (M+1); 1H NMR (400 MHz, DMSO-d6) δ 1.59 (m, 2H), 1.84 (t, J=7.2 Hz, 2H), 2.27 (t, J=7.6 Hz, 2H), 2.47 (t, J=4.8 Hz, 4H), 3.03 (t, J=4.8, 4H), 6.67 (m, 1H), 6.88 (m, 4H), 6.98 (d, J=9.2 Hz, 2H), 7.13 (m, 2H), 7.77 (s, 1H).

Provenance & Evidence